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On February 10, the latest research published in JAMA network open, a subsidiary of the Journal of the American Medical Association, pointed out that e-cigarettes can reduce harm. When smokers completely switch to e-cigarettes, their health will be improved. On the contrary, when e-cigarette users become smokers, the concentration of many carcinogen metabolites in their urine increases significantly, up to 621%.
Figure: Journal of the American Medical Association is one of the four famous medical weekly magazines in the world, and its subsidiary JAMA network open is a SCI journal
Supported by the National Institute on drug abuse (NIDA), the study tracked more than 3000 adult smokers in the United States for one year. Many smokers will experience a “transitional period” of mixed use of cigarettes and e-cigarettes before completely switching to e-cigarettes. The researchers first investigated this situation. The results showed that when smokers became dual users of mixed cigarettes and e-cigarettes, the metabolite concentration of tobacco harmful substances in their urine basically did not change, and the mixed mode did not make smokers healthier.
However, whether smokers or dual users, after completely switching to e-cigarettes, the metabolite concentration of tobacco harmful substances in their urine will be significantly reduced. Taking the primary carcinogen and tobacco specific nitrosamine highly related to lung cancer (the metabolite is NNAL) as an example, after smokers and dual users switch to e-cigarettes, the concentration of NNAL in their urine is reduced by 92% and 96% respectively, and the harm reduction effect is remarkable.
In order to further verify the conclusion, the researchers also conducted a reverse investigation on the situation of e-cigarette users after switching to cigarettes. The data show that when e-cigarette users become dual users, the concentration of nicotine metabolites in their urine increases three times. It’s even worse for e-cigarette users to become smokers: the concentration of polycyclic aromatic hydrocarbons metabolites in urine increased by 155%, and the concentration of VOC metabolites increased by 621%. PAHs and VOC are highly harmful carcinogens, which are associated with leukemia, bladder cancer, neurocognitive impairment, and many other diseases.
Re smoking cigarettes is expensive, and the mixed mode is not desirable. Only by completely switching to electronic cigarettes can the harm be reduced. In recent years, a number of studies around the world have confirmed this conclusion. The American Heart Association (AHA) pointed out in 2020 that smokers’ cardiovascular status has been improved after switching to electronic cigarettes. The common mixed use model can not reduce the risk of cardiovascular disease and is “completely ineffective”.
Figure: a research paper published by the American Heart Association, “the hazards of mixed use of cigarettes and e-cigarettes are the same as those of using only cigarettes”
“Our research confirms that e-cigarettes can play a positive role in the field of public health, but the mixed mode is limiting all this.” Neal l l benowitz, a tobacco control expert and one of the main authors of the paper, said. He hopes that smokers can have a more comprehensive understanding of the harm reduction effect of e-cigarettes: “don’t transition to the mixed mode. If you want to improve your health and really can’t quit cigarettes, you can completely switch to e-cigarettes.” More reading: NIH&FDA: research shows that adult smokers are more likely to quit their traditional cigarettes after starting smoking electronic cigarettes. New Zealand has issued the world’s most stringent tobacco control order: young people are “smoke-free” for life, but can buy electronic cigarettes “electronic cigarettes are more likely to cause diabetes”. The consequences of blindly banning the taste are very serious. New England Journal of Medicine: the success rate of quitting smoking with e-cigarettes is twice that of other methods. The latest research shows that the ban on the taste of e-cigarettes will lead to an increase in the smoking rate of teenagers. American Chemical Society: propylene glycol, the main component of e-cigarettes, can inhibit oral bacteria and inflammation. Inventory of seven outrageous research conclusions on e-cigarettes. How long have you been cheated? American CDC suggested that smokers “watch birds and quit smoking” was criticized: why not recommend e-cigarettes? These 10 reasons have made many people sing down the ban on e-cigarettes, which may lead to 150000 people losing their jobs and $8.4 billion in sales. People from all walks of life in the Philippines have called on smokers to switch to e-cigarettes: 16 million smokers have the opportunity to stay away from tobacco hazards. Toxicology research: some harmful substances are reduced by 89%! Scientists found new evidence to reduce the harm of e-cigarettes. After screening more than 5000 Global Studies, FDA confirmed that e-cigarettes are less harmful than cigarettes. The latest research supported by FDA: the smoking cessation effect of e-cigarettes is related to nicotine content
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