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The re infection of new crown mainly occurred in the elderly over 65 years old From The lancet

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Will people who have been infected with a new coronavirus be infected again? This problem has been concerned by scientists. Danish researchers published a study in the authoritative medical journal the lancet on Wednesday, revealing the reinfection of new crowns six months after their first infection. The results showed that most of the second infection cases occurred in the elderly over 65 years old.

The reinfection rate of the elderly was significantly higher than that of the young

Danish researchers studied the re infection rate of new crowns in 4 million people from September to December last year, and compared it with the new crown infection rate from March to may last year. Among the 11068 new crown infection positive patients detected from March to may last year, 72 people were positive again in the second test, with an average re infection rate of 0.65%, but the re infection rate of the elderly group over 65 years old reached 3.6%.

The finding is not entirely unexpected. Researchers say that as people get older, their immune response weakens, and antibody levels decline more quickly after infection than in young people. This study is also consistent with earlier studies. Previous studies have found that the reinfection rate after new crown infection is less than 1%, and the immune protection can last for five to six months.

But the latest study reveals significant differences in immune protection between young and old people. Young people who are first infected with the new coronavirus still have about 80% immune protection against the new coronavirus six months after infection, but older people aged 65 and above have only about 47% immune protection against re infection of the new coronavirus, the team wrote.

Dr Steen ethelberg, co-author of the report and researcher of the Danish National Institute of serum, said: “the results of this study emphasize that even if people have been infected with the new coronavirus, it is very important to take measures to ensure their own and others’ safety.”

The researchers are concerned about the difference of reinfection rate among different age groups. In a concurrent review of the study, Dr rosemary boyton and Daniel Altmann, immunologists at Imperial College London, said: “immune protection after initial infection has rapidly decreased from 80% in young people to 47% in people aged 65 and above, a significant difference that is more interesting than the data provided by previous studies. These data all confirm that the long-term protective immunity may not be achieved for the natural infection of new crown, and the only lasting solution is to adopt an efficient vaccination program. “

A viral immunology expert told China first finance and Economics: “although studies show that the elderly are at risk of reinfecting with the new crown, the more critical issue is whether they have severe conditions after reinfection.”

Dr Amy Edwards, an infectious disease expert at the University of Cleveland hospital in the United States, also said: “I think this study really highlights the importance of ensuring that all people over the age of 60 are vaccinated, whether or not they have been infected with the new coronavirus.”

The elderly need to be vaccinated faster

However, recent studies have found that the immune response of the vaccine in the elderly vaccinated population is also weak. Last week, researchers at the University Hospital of Dusseldorf in Germany tested people who received two doses of Pfizer vaccine and found that the immune response of the vaccine in the elderly was significantly weaker than that in the young.

The researchers studied 91 vaccinators under the age of 60 and 85 vaccinators over the age of 80. At 17 days after the second dose, nearly one-third (31%) of the elderly vaccinated did not produce antibodies that neutralized the new coronavirus, compared with only 2% of the population under 60. In addition, only 16% of people under 60 developed neutralizing antibodies after the first dose of vaccine. The test method used in this study was specific IgG antibody titer.

Ortwin Adams, co-author of the study at the University Hospital of Dusseldorf in Germany, believes that this result seems to indicate that the frequency of neutralizing antibody production in the elderly after vaccination is low, but it does not mean that the elderly will have serious complications if they are infected with the virus.

“According to previously published reports in Israel, England and Scotland, the incidence of hospitalization and serious diseases in people over 80 years old after their first vaccination is still significantly lower than those who are not vaccinated.” “This may mean that older people need to be vaccinated earlier than younger people to produce long-term protection,” Adam said

A limitation of the latest research in Denmark is that before the end of last year, the new coronavirus has not changed significantly. However, the latest research has found that the virus mutation seems to make people more likely to re infect the new coronavirus. However, there is no conclusive scientific evidence for the possible impact of the mutation on the re infection rate.

A new study published in the journal Cell on Friday showed that the neutralization efficiency of Moderna and antibodies induced by Pfizer / baintyco vaccine in neutralizing some of the most worrisome new crown variant strains has been greatly reduced. The neutralizing efficiency of neutralizing antibodies against the new crown variant strains found in Brazil has been reduced by five to six times, and the neutralizing efficiency against the variant strains found in South Africa has been reduced by 20% Times.

Currently, vaccine manufacturers, including Pfizer and Moderna, are working on a new version of the enhanced vaccine against the new coronavirus variant. Moderna has tested the enhanced vaccine on the first subject.

The head of cog-uk, Sharon peacock, recently said that as the mutation of the new coronavirus will speed up the spread of the virus and evade the immune protection of the vaccine, it is necessary to routinely vaccinate against the new coronavirus in the future. More reading: The Lancet: survey data show that smart phones can make people lose their sexuality Lancet: research shows that global pollution kills at least 9 million people every year Lancet: by July 2020, the global population will reach 7.8 billion Lancet: China is one of the five countries with the greatest medical progress Lancet: 28 million people worldwide super large scale analysis confirms: don’t drink a drop Drink! Lancet: 2.3 billion overweight people are found in the study Lancet: drinking alcohol increases the risk of hypertension and stroke Lancet: few cities can host the summer Olympic Games in 70 years One quarter of pregnancies in the world end due to abortion Lancet: research finds that happiness does not prolong life Lancet: China’s population is expected to drop to 730 million by 2100 Lancet: direct economic losses caused by extreme weather amounted to US $129 billion in 2016 Lancet: 9 million deaths in 2015 are related to pollution

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