Life data

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The following is the Which blood type of people live the longest? recommended by And this article belongs to the classification: Life data.

According to the ABO blood group classification system, human blood groups can be divided into four major categories – A, B, AB, O, and eight according to Rh antigen positive / negative.

Blood group classification, Walden University

The common or rare degree of a blood group varies with race, ethnic background and other factors. Most of the time, the purpose of blood type test is to donate blood safely or accept other people’s blood transfusion. Of course, it also has a fingerprint like ID function, which plays a key (but not absolute) role in determining whether the child belongs to himself or “the old king next door”. But what many people don’t know is that being in a certain blood type may mean that you are prone to some diseases, or that you may be a predictor of longer life. Because the ABO antigen of our blood group is not only expressed on the surface of red blood cells, but also exists in other human tissues, which provides a theoretical basis for various health outcomes of ABO blood group outside the blood system.

There are many conjectures about the relationship between blood group and health

People with type O blood have the lowest risk of heart disease

Earlier studies have shown that type a blood is associated with high levels of LDL (“bad”) cholesterol, while type AB blood is associated with inflammation, which are risk factors for heart disease. In 2012, researchers from the Harvard School of public health pooled data from two long-term studies, tracking 89500 adults over a 20-year period, and found that, compared with people with type O blood:

People with type AB blood are 23% more likely to have heart disease.

The risk of patients with type B blood increased by 11%.

People with type a blood increased the risk by 5%.

And the association did not change with the multivariable adjustment of other risk factors or dietary factors.

Risk ratio of coronary heart disease with different ABO blood groups (95% CI)

ABO Foundation Group and Risk of Coronary Heart disease along Two Prospective Cohort Studies.https http:// .1161/DEVELOPMENT

Regarding the potential mechanism of increased risk, the authors point out that plasma factor VIII VWF levels are about 25% higher in non-O group individuals than in O group patients. Elevated levels of factor VIII VWF have previously been identified as a risk factor for coronary heart disease.

Therefore, for people with non-O blood group, it is particularly important to maintain a heart healthy lifestyle, including improving cholesterol levels, quitting smoking, controlling hypertension and diabetes, exercising, maintaining a healthy weight, limiting drinking, and dealing with stress.

People with type a blood have a high risk of gastric cancer

There are many factors associated with a higher risk of cancer, so it is sometimes difficult to know which factors dominate. However, studies have confirmed that people with different ABO blood groups have different risk of cancer. People with type a blood have higher risk of gastric cancer, and people with non-O blood groups (a, B, ab) have higher risk of pancreatic cancer.

A cohort study from Taiwan included 339432 healthy people with laboratory based blood groups. After adjusting for age, gender, education, smoking, drinking, physical activity and body mass index, the study showed that compared with type O blood, type a blood was significantly associated with the risk of gastric cancer and mortality, while non-O blood was associated with the increased risk of pancreatic cancer. On the contrary, compared with type O, type AB blood was inversely correlated with the risk of renal cancer.

Part HRs screenshot of the incidence rate of cancer in general and specific etiology by ABO blood group.

ABO blood types and cancer risk—A cohort study of 339,432 subjects in Taiwan.doi: 10.1016/j.canep.2014.12.006

The findings from the American Journal of epidemiology also suggest that if the blood type is ab, the risk of gastric cancer is about 26% higher than that of B or O, and if the blood type is a, the risk is 20% higher.

Among other cancers, researchers from Cancer Research Institute of Chinese Academy of Sciences even confirmed that ABO blood group is an independent prognostic factor for ovarian cancer patients. By analyzing the relationship between ABO blood group and clinical characteristics of ovarian cancer patients, we found that the OS of ovarian cancer patients with B / AB blood group was poor, especially in FIGO I, IV and menopausal patients. Multivariate analysis shows that the association is independent.


Similarly, although we can’t change the blood type, we still have some ways to reduce the risk of cancer, such as paying attention to a healthy diet, eating more fruits, vegetables, whole grains, fish, etc., exercising regularly, and avoiding smoking. To avoid Helicobacter pylori infection is an important measure to prevent gastric cancer. Some experts believe that people with type a blood may overreact to this kind of bacteria, thus increasing the risk of cancer.

People with type O blood have a lower risk of Alzheimer’s disease

The ABO gene is associated with decreased brain function and memory. Compared with people with type O blood, people with type A, B and AB blood are 82% more likely to have cognitive and memory problems (which may lead to dementia).

A groundbreaking study by researchers at the University of Sheffield has revealed the role of blood groups in the development of the nervous system. In this study, the head of 189 healthy volunteers were scanned with magnetic resonance imaging (MRI), and the volume of gray matter in the brain was calculated. Through data analysis, it was found that people with type O blood had more gray matter in the brain (more gray matter in the posterior cerebellum), while people with type A, B or AB blood had smaller gray matter volume in the temporal and marginal regions of the brain, including the left hippocampus. These findings suggest that smaller gray matter volume is associated with non-O blood type.

With age, the volume of gray matter in the brain usually decreases, leading to an increased risk of diseases such as Alzheimer’s disease. The left hippocampus is one of the first parts of the brain damaged by Alzheimer’s disease.

The smaller gray matter volume is associated with non-O blood type

‘O’ blood type is associated with larger grey-matter volumes in the cerebellum. doi:10.1016/j.brainresbull.2015.05.005

Therefore, it is suggested that blood type may affect the development of nervous system, and the mechanism needs to be further explored in the future. In daily life, we still need to exercise regularly, avoid excessive stress, and get enough regular sleep to maintain strong cognitive function.

Having said so much, we all know that there are many factors affecting diseases, of which blood type is only one, and there may be contradictions in different studies. In the end, they may all have to return to a rigid index life span. Logically speaking, the above research has been extended to the potential association between ABO blood group and life span, but in the mid-20th century, some studies began to try to explain the differences in life span between individuals with different blood groups. So will people of different blood groups really live different lives? What kind of blood group lives longer?

Is blood type related to longevity?

In 1961, the first study found that 125 healthy elderly men (65-89 years old) had more type a blood. Eight years later, a study of 50 residents over the age of 90 found no correlation between ABO blood group and life expectancy. In a survey of German doctors over the age of 75, blood type O appears to be associated with longer life expectancy.

The findings of two studies on centenarians are contradictory. In 269 Japanese centenarians, the proportion of type B blood was higher (29.4%). In contrast, studies in the United States have concluded that type B is not so much associated with longevity as a sign of early death.

Therefore, the relationship between blood type and life span is still inconclusive. There are several possible explanations for these differences. For example, any identified association may be population or location specific. In addition, different conclusions may be affected by methodological differences, including potential pitfalls in this field. Sampling errors and racial or ethnic stratification may also be the reasons for different conclusions drawn by different research groups. Importantly, race and racial factors also lead to differences of ABO gene distribution as high as 5% – 20% in the population of the same country or even the same city. Similarly, sampling errors can lead to differences of up to 4% between samples from 1000 individuals.

If the association between blood group and life expectancy is to be clear, it is important to elucidate the mechanisms that contribute to this interaction, in part because any viable changes that could potentially have a negative impact on longevity can be evaluated. However, because ABO population is an unchangeable human characteristic, any research on the relationship between ABO blood group and life expectancy may only be attributed to “quite interesting” facts, rather than “clinical reality”.

“Blood type diet” overturned

Although there are many studies on the relationship between blood group and health, it is still too early to guide clinical practice. However, the so-called “blood type diet” has been widely spread. “Blood group diet” suggests that people with type a blood should mainly take plant-based diet, while people with type O blood should mainly take meat. This claim was rejected by a recent study published in the Journal of nutrition and diet, whose main findings were published in the November 30 issue of the Journal of the American Medical Association, network open.

The new study is based on a randomized controlled trial in which overweight participants without a history of diabetes were randomly assigned to either intervention or control groups in a 1:1 ratio. The intervention group followed a low-fat, plant-based diet. The control group did not change the diet, observed for 16 weeks. The results showed that plant-based diet could accelerate metabolism. Measured by the increase of postprandial calorie consumption, the intervention group had an average increase of 18.7% compared with the control group.

The clinical changes of overweight people receiving plant intervention diet in randomized clinical trials were classified by blood group

Blood Type Is Not Associated with Changes in Cardiometabolic Outcomes in Response to a Plant-Based Dietary Intervention.DOI:

Taking into account the potential link between blood group and diet, the researchers took an additional step to conduct a secondary analysis among participants in the intervention group of a 16 week randomized clinical trial. They analyzed whether the effects of plant-based dietary interventions on weight, blood lipids, and glycemic control were associated with ABO blood groups, and found no difference.

That is to say, a plant-based diet is good for people of all blood groups. People of all blood groups also benefit from vegetarianism based on eating fruits and vegetables, beans and whole grains, especially for overweight adults, and there is no evidence that a meaty diet is good for people of a certain blood group.

In short, at present, the relationship between blood type and health is becoming more and more clear in the increasingly mature research, but there are many contradictions in the research on the relationship between blood type and actual life span, and it may take some time to solve these mysteries. But we can be sure that no matter what health risks blood type indicates, we pay more attention to healthy diet and exercise in our daily life, which will always bring benefits to reduce the risk of various diseases.

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