“Being single for too long” or “breaking up frequently” are prone to high-level inflammation risk From Male only! BMJ
The following is the “Being single for too long” or “breaking up frequently” are prone to high-level inflammation risk From Male only! BMJ recommended by recordtrend.com. And this article belongs to the classification: Life data.
At the beginning of the new year, let’s have a confession——
Handsome boy, how about counting your previous girlfriends?
What? single AF (laughing but not talking)
Girls, did your “he” tell the truth? Maybe you can use “scientific means” to verify it!
On January 10, 2022, a project entitled “do partnership solutions and living alone effect system synchronous information?” The paper was published online in the Journal of Epidemiology & community health. This study draws an interesting conclusion: single middle-aged men who live alone for several years or have experienced multiple breakups / divorces have a higher risk of physical inflammation than ordinary people. be careful! This conclusion is only for men! (highlight)
Figure 1. Do partnership dissolutions and living alone affect systemic chronic inflammation? A cohort study of Danish adults (图片来源：BMJ Journals)
A total of 4835 participants, including 3336 men and 1499 women, were included in the study. They were all from the Copenhagen aging and middle life biobank (Camb), with an age range of 48 to 62 years. Among them, 4612 participants (3170 men and 1442 women) also provided information on the number of breakups. The way to detect the inflammatory level of subjects is to measure two key inflammatory markers in their blood – interleukin-6 (IL-6) and C-reactive protein (CRP).
In this experiment, the researchers investigated the living conditions of participants in the past 26 years (1986-2011). All participants were invited to participate in the follow-up of Camb, of which 31% also completed an additional questionnaire including health behavior, psychological factors and physical status, and conducted clinical tests.
It is regarded as a common and normal situation to live alone for less than 1 year (ha ha, do you feel bad?), Therefore, this kind of population is defined as the control group of this experiment. The results showed that compared with the “lucky ones” in the control group, men who lived alone for a longer time (single ≥ 7 years) had 12% higher IL-6 level and 11% higher CRP level; Compared with male participants who never lost their partner, the levels of IL-6 and CRP increased by 17% in men who experienced multiple emotional disputes (breakups ≥ 2 times).
Figure 2. Relationship between emotional breakdown / living alone for many years and two inflammatory markers in men and women (image source: BMJ Journals)
In addition, it is estimated that all men will be surprised and call it “unfair”: this correlation is only reflected in men, but this trend is not shown in female subjects – even if they are also single and live alone for several years or have experienced multiple breakups, female participants will not have elevated levels of inflammatory markers IL-6 and CRP.
The researchers have made several explanations for the causes of this phenomenon:
Firstly, it may be that men can generally get more health benefits from gender relations (in short, they are well taken care of), which means that once they are separated from their partners, their health level will show a great downward trend;
Secondly, after breaking up, men are more inclined to “externalizing” behavior, such as running out in the middle of the night to get drunk, which leads to the increase of inflammation level; Women prefer to digest their emotions silently, that is, internalizing problems, but the result is mental depression.
Figure 3. Men and women will show different behaviors after breaking up (picture source: pixabay)
Of course, this study contains fewer female participants than men, so if you want to more reasonably explain the reasons for this difference, more female subjects need to be included in the later stage to improve the conclusion.
At the same time, the researchers also found that for men, education was also associated with increased levels of inflammation.
Among the male participants who experienced multiple breakups, the higher the education, the greater the increase of IL-6 and CRP in their blood: the increase of IL-6 is the most significant among the men who have received higher education and have lived alone for at least 7 years; At the same time, the increase of CRP was the highest among men with higher education and living alone for 2 ~ 6 years. On the contrary, in men and women with lower education, no inflammatory markers were found to be particularly vulnerable to the number of single years or breakups.
Figure 4. Combined effects of male emotional breakdown / years of solitude and the highest level of education on inflammatory markers (image source: BMJ Journals)
However, the researchers also admit that this is only an observational study, so the causal relationship between singleness and inflammation is not 100% certain. Although systemic chronic inflammation (SCI) is classified as low grade inflammation (low grade), it does not seem to have a significant impact on human health, but it will deteriorate with age and is considered to be a key factor in several age-related diseases, such as cancer, cardiovascular disease and type 2 diabetes. Because of its significant clinical relevance, it is likely to be one of the risk factors for increasing mortality.
To sum up, from the perspective of everyone’s physical and mental health and happiness, avoid “house” and “slag”. It can be said to be a four word truth!
reference material:
1.BMJ: Do partnership dissolutions and living alone affect systemic chronic inflammation? A cohort study of Danish adults
https://jech.bmj.com/content/early/2022/01/04/jech-2021-217422#block-system-main
2.EurekAlert: Years lived alone and/or serial break-ups strongly linked to inflammation in men
https://www.eurekalert.org/news-releases/939439
Author Xu ChuChu
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