Research shows that “medicine is better than food”!

The following is the Research shows that “medicine is better than food”! recommended by recordtrend.com. And this article belongs to the classification: Life data.

As the saying goes, “man is like food”. The food we eat is closely related to our health. But this concept is usually forgotten by everyone. Only when health lights up the red light can we know that everything is just “logical”. Others always hope to reverse bad eating habits, maintain health, or delay aging through various drugs without changing eating habits.

Recently, in a research report published in the international journal cell metabolism, scientists from the University of Sydney and other institutions studied and compared the effects and differences of diet and drugs on the internal working mechanism of cells. It was found that nutrition may have a greater impact. The researchers pointed out that in controlling diseases such as diabetes, stroke and heart disease, human diet structure or composition may be more powerful than drugs.

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By studying in mice, researchers found that nutrition (including total calories and macronutrient balance) had greater effects on aging and metabolic health than three drugs commonly used to treat diabetes and slow down aging.

The study, based on pioneering work done by researchers on mice and humans, confirmed that dietary and specific proteins, fats and carbohydrates play a protective role in preventing aging, obesity, heart disease, immune dysfunction and the risk of metabolic diseases such as type 2 diabetes.

Researcher Professor Stephen Simpson said that drugs may also target the same biochemical pathways as nutrients. At present, we have conducted a large number of studies and found that some drugs may improve the body’s metabolic health and aging without dietary changes.

Diet is actually a powerful “drug”. However, the drugs used at present do not consider whether and how they interact with the body’s diet structure, even if these drugs are designed to act on the same pathway as diet and the same nutritional signal pathway. So researchers began to study whether drugs or diet are more powerful in reshaping nutritional perception and other metabolic pathways, and whether the interaction between drugs and diet can make it more effective or ineffective. The researchers found that dietary composition has a stronger effect than drugs, and drugs will largely inhibit the response of diet rather than reshape the response of diet.

Considering that humans and mice share basically the same nutritional signaling pathway, researchers have shown that people may be able to obtain better benefits from improving metabolic health by changing diet, rather than taking the drugs provided in this study.

Then the researchers conducted a complex mouse study. They conducted 40 different treatments. Each treatment contained different protein, fat and carbohydrate balance, calories and drug composition. This study aims to analyze the effects of these anti-aging drugs on the liver, which is the key organ involved in metabolic regulation.

A key advantage of this study is that researchers use the nutritional geometric framework developed earlier. This framework may help researchers analyze how the mixture and interaction of different nutrients affect body health and disease occurrence, rather than focusing on one nutrient alone, which is a major limitation of other nutrition studies. The findings may help researchers understand the molecular mechanisms that link what we eat to how we age. The researchers found that calorie intake and the balance of macronutrients (protein, lipid and carbohydrate) in the diet may have a significant impact on the liver.

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Protein and total calorie intake will not only have a strong impact on metabolic pathways, but also have a corresponding impact on the way cells operate. For example, the level of protein intake will affect the activity of mitochondria, which may have a downstream effect, because the level of protein intake and dietary energy may affect how cells convert genes into different proteins that help cells maintain proper function and make new cells. These processes may be related to aging. In contrast, drugs mainly inhibit the metabolic response of cells to diet, rather than fundamentally reshape their function. The researchers also found that there may be some more specific interactions between the biochemical effects of drugs and dietary composition.

An anti-aging drug may have a greater impact on cell changes caused by dietary fat and carbohydrates, while cancer and other diabetes drugs may block the effect of dietary protein on the energy producing mitochondria.

Researcher Professor David Le couteur said that although this study is very complex, it reveals the importance of studying different diets at the same time, rather than comparing the differences between several different diets. This method is the only way we can analyze the interaction between diet, body health and physiological characteristics.

We all know that the diet intake by the body will affect the body’s health, but this study reveals how these foods significantly affect the process of operation in the body’s cells, which may help to explain the molecular mechanism of diet affecting the body’s health and aging.

In conclusion, the results of this study show that the dietary group has a strong impact on the proteome of the liver, not only the metabolic pathway, but also the basic physiological processes such as mitochondrial function and RNA splicing.

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